Prisco’s Week 2 NFL picks: Saints beat Tom Brady again, Giants go 2-0 with win over Panthers

The first week of the NFL season is always so unpredictable. So I’ll be happy with my first week of picks after seeing what happened in week 1.

I went straight out 7-8-1 which stinks. I went 8-8 against the spread, which is so, so. But the great news is that I went 5-1 with my best bets as part of the Pick Six Podcast. And if I hadn’t added the Jacksonville Jaguars late, it would have been clean. Even that looked good for a while.

So let’s get back to it in what I’m calling the week of the NFL equalization. Teams that looked bad in Week 1 probably won’t look that way in Week 2, while the opposite is likely true for some of the winners. It won’t always play out that way, but I think it will this week in a lot of the games.

It’s time to bring back the outright record, but most of all let’s stay hot with the best bets.

Thursday, 8:20 PM ET (Amazon Prime)

Featured game | Kansas City Chiefs vs. Los Angeles Chargers

This is the Justin Herbert vs. Patrick Mahomes Game of the Week. It’s a treat every time they meet, and Arrowhead will rock on Thursday night. The Chiefs rolled against the Cardinals with Mahomes lighting things up. But the Chargers can rush the passer with Khalil Mack and Joey Bosa. Look for a high-scoring game with the Chiefs winning close.

Select: Bosses 31, Chargers 30

Sunday, 1 p.m. ET (CBS, Paramount+)

Featured game | Baltimore Ravens vs. Miami Dolphins

The Dolphins and Ravens both won in impressive fashion last week, but now Miami hits the road for the first time. The Dolphins dominated the Ravens last year at home, but this will be different. The Ravens and Lamar Jackson get the best of the Dolphins.

Select: Ravens 27, Dolphins 20

Sunday, 1 p.m. ET (CBS, Paramount+)

Featured game | Cleveland Browns vs New York Jets

The Browns will be facing a familiar quarterback this week in Joe Flacco. He wasn’t good last week in the Jets’ loss to the Ravens. The Browns had a close win against Carolina last week, but they’re at home this one and Jacoby Brissett will be better in his second start for the Browns. They go up 2-0.

Select: Browns 24, Jets 13

Sunday, 1 p.m. ET (Fox, FuboTV)

Featured game | Detroit Lions vs. Washington Commanders

The Commanders are coming off a home win over the Jaguars where Carson Wentz led them to the winning score late. The Lions looked good offensively against the Eagles, but the defense was terrible. This could turn out to be a shootout. Washington is the better team and I think that will show. Commanders take it.

Select: Commanders 31, Lions 27

Sunday, 1 p.m. ET (CBS, Paramount+)

Featured game | Jacksonville Jaguars vs. Indianapolis Colts

The Colts haven’t won in Jacksonville since 2014 and lost there last year in the final week, costing them a playoff spot. They also play back-to-back road games while Jacksonville plays at home. That’s a big advantage for the Jaguars. The Colts rallied to tie the Texans last week, but they won’t rally to win this time. The Jaguars will get their first win.

Select: Jaguars 26, Colts 23

Sunday, 1 p.m. ET (Fox, FuboTV)

Featured game | New Orleans Saints vs. Tampa Bay Buccaneers

The Bucs play back-to-back road games after a Sunday night game that is always tough. But they’ve also been hit on offense in a big way. The Saints defense chases Tom Brady when his line is healthy, which it isn’t. Expect the Saints defense to come up big here after struggling last week. Saints take it.

Select: Saints 23, Bucs 17

Sunday, 1 p.m. ET (Fox, FuboTV)

Featured game | New York Giants vs Carolina Panthers

The Giants did some good things rallying late to beat the Titans on the road. Saquon Barkley was special. He will once again carry the team here against a Carolina team that lost last week to the Browns. Giants lead 2-0. Can you believe?

Select: Giants 23, Panthers 17

Sunday, 1 p.m. ET (CBS, Paramount+)

Featured game | Pittsburgh Steelers vs. New England Patriots

The Patriots play back-to-back road games after a terrible performance in Miami. The Steelers are playing their home game after upsetting the Bengals. But the Steelers will be without TJ Watt, which matters a lot. The defensive dynamic is changing. The Patriots will hang around in this one as the offense finally shows some life. Then they will win it late.

Select: Patriots 21, Steelers 20

Sunday, 4:05 p.m. ET (Fox, FuboTV)

Featured game | Los Angeles Rams vs. Atlanta Falcons

The Rams will rest 10 days after a terrible performance against the Bills. Sean McVay is too good a coach to continue this losing streak. The Falcons played well in the loss to the Saints in a game they probably should have won. It’s a long trip against a good team that will be focused. The Rams take it big.

Select: Rams 31, Falcons 17

Sunday, 4:05 p.m. ET (Fox, FuboTV)

Featured game | San Francisco 49ers vs. Seattle Seahawks

The Seahawks are 1-0 while the 49ers are 0-1. Who saw this after week 1? Seattle played well in upsetting the Broncos on Monday night, but they now head into a short week. This is a challenge. The 49ers didn’t play well in poor conditions at Soldier Field in the loss to the Bears, but that will change here. Trey Lance drives it.

Select: 49ers 29, Seahawks 23

Cincinnati Bengals (-7.5) at Dallas Cowboys

Sunday, 4:25 pm ET (CBS, Paramount+)

Featured game | Dallas Cowboys vs. Cincinnati Bengals

The Bengals get a break by facing Cooper Rush rather than Dak Prescott. It took Joe Burrow a while to get going against Pittsburgh after spending much of training camp, but he shook off the rust in the second half. I think that carries over. The Cowboys are too limited on offense. Bengals win it.

Select: Bengals 27, Cowboys 20

Houston Texans at Denver Broncos (-10)

Sunday, 4:25 PM ET (CBS, Paramount+)

Featured game | Denver Broncos vs. Houston Texans

The Broncos are playing their home game after losing Monday night to the Seahawks in a must-win game. The Texans played well in tying the Colts last week, but it will be more of a challenge on the road. I think they can hang on in this one, but the Broncos will win it late.

Select: Broncos 24, Texas 21

Sunday, 4:25 PM ET (CBS, Paramount+)

Featured game | Las Vegas Raiders vs. Arizona Cardinals

The Raiders lost to the Chargers, but they played well. The Cardinals lost to the Chiefs and played terrible football. Now they are hitting the road for the first time. The Cardinals just don’t feel like they’re a good team. Derek Carr illuminates them.

Select: Raiders 34, Cardinals 17

Sunday, 8:20 p.m. ET (NBC, FuboTV)

Featured game | Green Bay Packers vs. Chicago Bears

The Packers were awful, losing to the Vikings, while the Bears shocked the 49ers in a heavy rain storm. This is the right play for the Packers. Aaron Rodgers and the passing game will drive him, and the defense will dominate Justin Fields and the Bears offense.

Select: Packers 34, Bears 14

Tennessee Titans at Buffalo Bills (-10)

Monday, 7:15 p.m. ET (ESPN, FuboTV)

Featured game | Buffalo Bills vs. Tennessee Titans

The Titans are coming off a brutal loss to the Giants where they blew a big lead. They now head north to play a Bills team that will be off 11 days. This is important. Buffalo has had trouble with the Titans in recent years, but that won’t be the case here. Josh Allen continues to put up big numbers.

Select: Bills 33, Titans 19

Minnesota Vikings vs Philadelphia Eagles (-2.5)

Monday, 8:30 p.m. ET (ESPN, FuboTV)

Featured game | Philadelphia Eagles vs. Minnesota Vikings

This is one of the best games of the week, with two 1-0 teams coming off impressive wins. Minnesota’s defense was outstanding last week against the Packers, but this is a different style of offense. The Eagles will score a lot of points here, but the Vikings will also get theirs. It will be a penalty shootout and the Eagles will make the most of it.

Select: Eagles 32, Vikings 26

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